Cystistatin 60 count


Support for the urinary tract during acute urinary tract inflammations.

Uva Ursi- 20% arbutin: 

  • The medicinal portion is the dried leaves, which contain arbutin, methylarbutin, flavonoids, allantoin, tannins, organic acids, volatile oils, resins and others
  • Arbutin is converted in the alkaline urine to hydroquinone , a potent disinfectant.
  • Positive Commission E Monograph for inflammatory disorders of the urinary tract- with confirmed antibacterial activity
  • Antimicrobial activity against:

E.coli, Enterobacter, Helicobacter pylori, Klebsiella, Shigella sonnei, Shigella flexneri, Listeria monocytogenes, Pseudomonas aeruginosa.1-4

Berberine Sulfate:

  • Berberine concentrates in the bladder upon ingestion of Goldenseal
  • Berberine sulfate blocks the adhesion of uropathogenic E. coli by suppressing the synthesis and assembly of adhesionmolecules (fibriae).5Marshmallow Root:
    • Used traditionally for its soothing demulcent properties. As the urinary tract lining is inflamed during infection, this activity is likely to soothe these membranes.
    • Commission E approves Marshmallow for its demulcent activity-in the irritation of the oral and pharyngeal mucosa and associated dry cough. And Mild inflammation of the gastric mucosa.Bladderwrack:
    • Bladderwrack is a perennial seaweed found along the shores of Europe and America. It has been used for conditions associated with the bladder, although its name is probably derived from the bladder-like vesicles along its fronds.
    • Bladderwrack has been used historically as a diuretic as well as for cases of cystic irritations and chronic inflammations of the bladder.Celery Seed Extract (Apium graveolens):
  • Celery belongs to the same family (umbelliferae) as carrots, parsley and fennel. While most people associate celery with its stalks, celery seed has been used for centuries and still is today for its soothing, cleansing, diuretic and antiseptic qualities.6
  • The German Commission E indicates that celery preparations are used as diuretics, for “blood purification” and for other conditions.7
  • Celery seed contains a number of constituents that have antibacterial properties. It also is a diuretic, which increases urine output to clear bacteria from the urinary tract.8,9
  • An extract of the seed from celery (Apium graviolens), and fractions thereof, have been found to possess anti-inflammatory activity, gastro-protective activity, and anti-Helicobacter pylori activity.10


  1. Jahodar L, Jilek P, Paktova M, Dvorakova V. [Antimicrobial effect of arbutin and an extract of the leaves of Arctostaphylos uva-ursi in vitro]. Cesk Farm. Jun 1985;34(5):174-178.
  2. Moskalenko SA. Preliminary screening of far-eastern ethnomedicinal plants for antibacterial activity. J Ethnopharmacol. Mar 1986;15(3):231-259.
  3. Annuk H, Hirmo S, Turi E, Mikelsaar M, Arak E, Wadstrom T. Effect on cell surface hydrophobicity and susceptibility of Helicobacter pylori to medicinal plant extracts. FEMS Microbiol Lett.Mar 1 1999;172(1):41-45.
  4. Park SF. The repression of listeriolysin O expression in Listeria monocytogenes by the phenolic beta-D-glucoside, arbutin. Lett Appl Microbiol. Oct 1994;19(4):258-260.
  5. Sun D, Abraham SN, Beachey EH. Influence of berberine sulfate on synthesis and expression of Pap fimbrial adhesin in uropathogenic Escherichia coli. Antimicrob.Agents Chemother.1988;32(8):1274-1277.
  6. Newall C, Anderson L, Phillipson J, eds. J.Herbal medicines: A guide for health-care professionals. London: The Pharmaceutical Press; 1996.
  7. Blumenthal, Busse, Goldberg, et al. Celery. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines1998:320.
  8. Celery Seed. Integrative Medicine Access
  9. Johnston L. Urinary Tract Infections
  10. Powanda M, Rainsford K. A toxicological investigation of a celery seed extract having anti-inflammatory activity. Inflammopharmacology 2011;19(4):227-233.

These statements have not been evaluated by the food and drug administration.  This product is not intended to diagnose, treat, cure or prevent any disease.  The information presented here is intended to assist health care professionals to make informed decisions about recommending this product safely and effectively.


System Support

Urinary Tract Support

Uva Ursi

The leaves of uva ursi (Arctostaphylos uva ursi) have been used for centuries in herbal medicine to support the health of the urinary tract. The medicinal portion of uva ursi is the dried leaves, which, in addition to providing arbutin, have methylarbutin, flavonoids, allantoin, tannins, gallic and ellagic acids, volatile oils and a resins (urvone). Each of the components in uva ursi leaf work synergistically with arbutin to promote healthy bacteria balance in the urinary tract. Additionally, the components of the uva ursi leaf prevent the breakdown and improve absorption of the arbutin molecule. When arbutin remains intact, it is excreted through the kidneys and provides microbial support for urinary tract mucous membranes. Research has demonstrated uva ursi’s ability to promote microbial balance in the bladder and ability to flush out the urinary tract.

Berberine Sulfate 

Berberine sulfate is an alkaloid sulfate extracted from the roots and barks of many plants and possesses microbial-balancing properties. Berberine sulfate’s main mechanism of action is blocking the adhesion of organisms to host cells. Berberine sulfate demonstrates excellent broad-spectrum support for maintenance of a healthy urinary tract.

Supplement Facts

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving:
Uva Ursi Leaf Extract (Standardized to contain 20% Arbutin) 650 mg
Berberine Hydrochloride Hydrate 200 mg
Marshmallow Root 150 mg
Bladderwrack Leaf 80 mg
Celery Seed Extract 80 mg

Other Ingredients: Natural Vegetable Capsules, Magnesium Stearate, and Silicon Dioxide.

Caution: Do not consume this product if you are pregnant or nursing. Consult your physician for further information.



As a dietary supplement, 1-2 capsules three times per day or as recommended by your health care professional. Not for long term use.

Contraindications, Adverse or Other reactions:

Class 1. Do not consume this product if you are pregnant or nursing. Levothyroxine is used for low thyroid function. Taking celery seed along with levothyroxine might decrease the effectiveness of levothyroxine. It is not clear why this interaction might oc- cur. Celery might also increase your sensitivity to sunlight. Taking celery along with medications that increase sensitivity to sunlight could increase the chances of sunburn, blistering, or rashes on areas of skin exposed to sunlight


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