Detoxication Factors™ provides comprehensive phase I and phase II support for detoxification processes. These phases seen in the liver are essential in a thorough detoxification regiment.*
Liver detoxication occurs in two phases. During Phase I, enzymatic chemical reactions change both exogenous substances (e.g., prescription medications and pesticides) and endogenous toxins (e.g., hormones) into more water-soluble metabolites. In Phase II detoxication, the liver conjugates these metabolites to protective compounds— such as glucuronides, glutathione, sulfonates, and amino acids—that make them less harmful and easier to eliminate.1
Developed to support healthy Phase I and II detoxication pathways in the liver, Detoxication Factors provides an expertly formulated combination of 38 ingredients. It can be used for everyday nutritional support, for periods of increased oxidative stress and targeted cleansing, and can be incorporated into individualized endocrine, cardiovascular, or cellular support protocols.*
Detoxication Factors contains:
- Antioxidants: nutrients that have been clinically shown to defend against oxidation and free radical damage*
- Conjugating agents: compounds that bind and/or support the conversion of fat-soluble toxins for elimination*
- Nutritional cofactors: vitamins, minerals, enzymes, botanical extracts, and other nutrients that participate in metabolic defense, repair, and restoration*
1. Nick GL. Detoxification overview. In: Clinical Purification: A Complete Treatment and Reference Manual Brookfield, Wis: Longevity Through Prevention Books; 2001:167-178.
* For dietary supplements: this statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Phase 1 and Phase 2 Detoxification, Liver Detoxification
Amount per 2 capsules
Total Carbohydrate 2 g
Vitamin A (75% as beta carotene and as retinyl palmitate) 6,668 IU
Vitamin C (as magnesium ascorbate) 167 mg
Vitamin E (as d-alpha tocopheryl succinate) 83 IU
Thiamin (as thiamin HCl, thiamin pyrophosphate) 8.7 mg
Riboflavin (as riboflavin-5-phosphate) 8.3 mg
Niacin 10 mg
Vitamin B6 (as pyridoxal-5-phosphate) 10 mg
Folic Acid 200 mcg
Vitamin B12 (as methylcobalamin) 42 mcg
Biotin 66 mcg
Pantothenic Acid (as calcium pantothenate) 33 mg
Magnesium (as magnesium citrate, malate, ascorbate) 78 mg
Zinc (as zinc picolinate) 10 mg
Selenium (as L-selenomethionine) 66 mcg
Copper (as copper sebicate) 334 mcg
Manganese (as manganese glycinate) 2 mg
Molybdenum (as molybdenum citrate) 50 mcg
Calcium D-Glucarate 66 mg
Choline (as choline bitartrate) 66 mg
Glycine 66 mg
L-Glutamic Acid HCl 66 mg
L-Glutamine 66 mg
L-Methionine 66 mg
L-Taurine 66 mg
NAC (as N-acetyl L-cysteine) 66 mg
Quercetin (dihydrate) 66 mg
Broccoli (Brassica oleracea italica) Sprout Powder (standardized to contain 0.4% sulforaphane) 33 mg
Inositol 33 mg
L-Ornithine HCl 33 mg
L-Carnitine (as L-carnitine tartrate) 16 mg
L-Glutathione, reduced 16 mg
L-Histidine 16 mg
L-Serine 16 mg
Milk Thistle (Silybum marianum) Seed Extract 16 mg
Turmeric (Curcuma longa) Extract (standardized to contain 95% curcuminoids) 16 mg
Coenzyme Q10 (CoQ10) (ubiquinone) 8.4 mg
Green Tea (Camellia sinensis) Extract (standardized to contain 80% catechin and 98% polyphenols) 8.3 mg
Grape (Vitis vinifera) Seed Extract (90% polyphenols including procyanidolic oligomers) 3.4 mg
Catalase 16 mcg
Other ingredients: gelatin, cellulose, silicon dioxide. Contains no sugar, salt, yeast, wheat, gluten, soy, dairy products, artificial colors, flavors or preservatives.
Take 1 or 2 capsules three times daily between meals, or as recommended by your healthcare professional.
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
At Integrative Therapeutics, we continue to set new standards for quality. We are one of only a few companies that manufacture dietary supplements and over-the-counter (OTC) medicines, dictating our status as a drug GMP audited facility. We have meticulous quality standards, rigorous testing requirements, and vigilant audits and inspections. Our products are safe, and our labels are accurate. Every product we sell is consistent, batch to batch, bottle to bottle, and capsule to capsule.
Deciphering Quality Standards Throughout the dietary supplement industry, manufacturers claim that product quality is the cornerstone of their business. As a drug GMP audited facility, Integrative Therapeutics views quality as more than propaganda. It is the foundation upon which our entire operation is built – it is that which sets us apart in the dietary supplement industry.
Good Manufacturing Practices (GMPs): Defined Good Manufacturing Practices refer to a set of requirements and expectations by which dietary supplements and their ingredients must be qualified, sampled, laboratory tested, manufactured, packaged, released for sale, and stored in order to ensure consistent quality. Through the execution of GMPs, manufacturers are expected to verify the identity, purity, strength, and composition of each of the dietary supplements produced. A company’s specific GMPs are captured in their written documentation which includes, but is not limited to the following:
Standard Operating Procedures (SOPs): SOP documentation is required for all aspects of manufacturing, from receipt of materials to processing to packaging, as well as all maintenance, housekeeping, and disposal procedures. Our Compliance: nearly 900 written SOPs.
Specifications: Specifications that define rigorous identification and testing requirements of all products, ingredients, and even packaging components, like cotton and desiccants.
Our Compliance: over 5,000 specifications.
Master Manufacturing Records: Records designed to assure consistent product identity, safety, potency, and bioavailability.
Our Compliance: we maintain records for every material produced. Laboratory Records Records which include written test methods and data from each lot of raw material and each finished product.
Our Compliance: over 100,000 tests annually.